Biochemical Efficacy and Safety Trial of vitamin D (BEST-D)

Not Applicable

Completed

• Conditions: Safety and efficacy of vitamin D; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN07034656
• Lead Sponsor: niversity of Oxford (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04-12
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

1. Age = 65 years
2. Living in the community and ambulatory

Exclusion Criteria

1. Nursing home residents
2. Regular use of vitamin D supplements with >400 IU (10 µg) vitamin D daily
3. Use of alendronate, risedronate, zoledronic acid, parathyroid hormone, or calcitonin
4. Medically diagnosed dementia
5. History of hypercalcaemia, hyperparathyroidism, lymphoma, sarcoidosis, active tuberculosis
6. History of renal calculus
7. Known to be poorly compliant with clinic visits or with taking medication
8. Recent history of alcohol or substance misuse or abuse
9. Medical history that might limit the ability of the subject to take the study treatment for the duration of the study (e.g. terminal illness)
10. Regular prescribed calcium supplements

Study & Design

• Study Type: Interventional
• Study Design: Not specified