The acute effects of triacylglycerol structure of palmitic acid rich fats on postprandial changes in lipid and glucose metabolism: a randomised cross-over trial

King's College London (UK)0 个研究点目标入组 48 人开始时间: 2009年3月13日最近更新: 2015年1月13日

适应症

试验速览

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•1. A reported history of heart disease, diabetes, cancer, kidney, liver or bowel disease (healthy volunteers are required)
•2. Current cigarette smoker
•3. History of substance abuse or alcoholism (previous weekly alcohol intake greater than 60 units/men or 50 units/women)
•4. Current self-reported weekly alcohol intake exceeding 28 units
•5. Unwilling to follow the protocol and/or give informed consent
•6. Weight change of greater than 3 kg in preceding 2 months
•7. Body mass index (BMI) less than 20 and greater than 35 kg/m^2
•8. Blood pressure greater than 160/90 mmHg
•9. Fasting blood cholesterol greater than 7.8 mmol/l, fasting plasma triacylglycerol concentrations greater than 3 mmol/l, or fasting plasma glucose greater than 7 mmol/L
•10. Presence of gastrointestinal disorder or use of a drug, which is likely to alter gastrointestinal motility or nutrient absorption
•11. Greater than or equal to 20% 10-year risk of cardiovascular disease (CVD) as calculated using the risk calculator
•12. Vegetarian dietary practices
•13. Pregnant women

发起方

King's College London (UK)