Effect of asymmetrical nasal high flow therapy on nasal airflow

Not Applicable

• Conditions: Respiratory disease; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12623000235606
• Lead Sponsor: Massey University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-03-06
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Participants must be healthy, aged between 18 and 35 years and free of nasal/upper airway pathophysiology.

Exclusion Criteria

Participants will be excluded if:
-They have any allergies
- They have recently (in the last month) had any illness or infection.
-They have ever had any surgery or trauma to their nose.
-They suffer from asthma or any other respiratory disease.
-They have ever been told that they snore loudly.
-They have been told that they stop breathing during their sleep.
-They have a deviated septum.
-They have difficulty breathing through their nose.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
asal, oral resistance and total resistance: This will be measured using a pressure transducer and flow head, and assessed as a composite outcome.[Resistance will be measured before NHF therapy/control (baseline), and after three hours (post).];Nasal volume will be performed using acoustic rhinometry [Nasal volume will be measured before NHF therapy/control (baseline), and after three hours (post).]

Secondary Outcome Measures

Name	Time	Method
Self reported nasal patency will be assessed via a questionnaire asking participants to rate how patent they feel their nostrils are[The questionnaire will be administered before NHF therapy/control (baseline), and after three hours (post).];Nasal temperature will be assessed using a thermocouple placed inside the nostrils. [Pressure will be measured continuously during the 3 hour intervention period];Pressure inside the nostrils will be measured using a pressure transducer.[Pressure will be measured continuously throughout the 3 hour intervention period.]