Study of the Variations of the Blood Pressure After Nephrectomy for Renal Cancer (VAPANCR)

Not Applicable

• Conditions: Renal Cancer; Nephrectomy; Blood Pressure
• Interventions: Biological: Renin measurement

• Registration Number: NCT03218319
• Lead Sponsor: University Hospital, Angers

Brief Summary

This study evaluates the impact of nephrectomy in renal cancer on blood pressure and renal function. The patients will have a follow-up of their blood pressure and renal function until 6 months after their operation.

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-07
• Study Start: 2017-07
• Study First Submitted: 2017-07-11
• Study First Submitted QC: 2017-07-12
• Last Update Submitted: 2017-07-12
• Study First Posted: 2017-07-14
• Last Update Posted: 2017-07-14
• Primary Completion: 2018-12
• Study Completion: 2018-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Nephrectomy programmed for located renal cancer

Exclusion Criteria

• Patients with metastatic renal cancer
• Incapacity to use a self-measurement tensiometer
• Patients treated for high blood pressure
• Patients with laxative

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
All patients	Renin measurement	-

Primary Outcome Measures

Name	Time	Method
Blood pressure change	One time before the operation and twice after : 1 month and 6 months	preoperative and postoperative measurements of blood pressure

Secondary Outcome Measures

Name	Time	Method
Renal function	One time before the operation and one after 6 months	preoperative and postoperative measurements of renal function with measurements of renin activity and the glomerular filtration rate.
Cardiovascular risk	A clinical exam will perform before the surgery and 1 month and 6 months after	Study the occurence of cardiovascular risk after nephrectomy