Sustainable household contact tracing and screening for tuberculosis patients and families in Blantyre, Malawi
- Conditions
- Infections and InfestationsTuberculosis
- Registration Number
- ISRCTN81659509
- Lead Sponsor
- Malawi National Tuberculosis Programme (Malawi)
- Brief Summary
2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36074775/ (added 09/09/2022)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 428
1. Pulmonary tuberculosis (PTB) patients registering at Queen Elizabeth Central Hospital (QECH), Malawi
2. Self-report of one or more under 5 year old household contact
3. Residence within Blantyre
4. Able and willing to provide written consent to participate in the study, including a 3 month household visit
5. If an inpatient: likely to be discharged within a two week period
Contacts will be defined as members of the same household (defined as sharing meals) or other residents of the same dwelling who share physical space such as sleeping or living rooms. Participation by contacts will be through oral consent, using a patient information leaflet.
1. Unable or unwilling to provide informed consent
2. Hospitalised patients who are unlikely to be discharged within a two week period (e.g due to retreatment requiring on TB treatment, and if transferred in and out of QECH)
3. Membership of a household that has already been recruited into the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. The prevalence of bacteriologically confirmed TB in adult and child contacts diagnosed within three months of the diagnosis of the index case<br> 2. The proportion of child contacts under 5 year who start IPT within three months of the diagnosis of the index case<br>
- Secondary Outcome Measures
Name Time Method The proportions of contacts under 5 years old who initiate and complete 6 months of IPT