Preoperative FibroScan Grading of Liver and Related Perioperative Morbidity during Laparoscopic Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- 1. Fibro scan as preoperative tool to quantify non-alcoholic fatty liver disease in patients subjected to laparoscopic surgery.
研究概览
简要总结
FibroScan® is superior to ultrasound for the detection of liver scarring and therefore may be used to determine if cirrhosis or advanced fibrosis is present at the initial assessment and whether it has developed during follow up because of disease progression. In this study, we are trying to detect whether laparoscopy have deteriorating effect on liver function in patients with pre-existing hepatic disease and whether fibro scan can be a reliable tool for detecting acute changes in patients with preexisting hepatic disease and its correlation with liver function test and color doppler. There has been few studies on comparison between color doppler and fibro scan in patients with cirrhosis and non-alcoholic steatohepatitis(NASH) .To best of our knowledge , this study has not been conducted in Indian population
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 25.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Duration of surgery: at least >2 h Patients with Clinical /Biochemical / Fibro scan diagnosed liver pathology.
排除标准
- •Patient refusal
- •Patients < 25 years of age and >65 years of age
- •ASA physical status 3 and 4
- •Pregnancy
- •Patients with advanced liver disease
- •Patient with confirmed diagnosis or active malignancy
- •Laparoscopic surgery converted to open surgery
- •Major hepatobiliary damage while operating.
结局指标
主要结局
1. Fibro scan as preoperative tool to quantify non-alcoholic fatty liver disease in patients subjected to laparoscopic surgery.
时间窗: Preoperative(baseline), POD-0,POD-7
2. To compare the effects of laparoscopic V/S non- laparoscopic abdominal surgery on liver function test in subclinical liver disease patients by FIBROSCAN
时间窗: Preoperative(baseline), POD-0,POD-7
次要结局
- To study the correlation between Fibro scan with Liver Function Test & Color Doppler in assessing hepatic changes during laparoscopic surgery(Preoperative baseline , POD -0 & POD-7)
研究者
Sona P
AIIMS, Mangalagiri