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Clinical Trials/NCT03581110
NCT03581110
Completed
Not Applicable

CODP Imaging From a Dose Perspective - Effective Organ Doses of a Combined Inspiration-expiration Protocol on a 3rd Generation Dual-source CT

Universitätsmedizin Mannheim0 sites1,957 target enrollmentAugust 2014
ConditionsRadiation

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Radiation
Sponsor
Universitätsmedizin Mannheim
Enrollment
1957
Primary Endpoint
organ specific radiation doses
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The noncontrast-enhanced chest computed tomography (CT) is an emerging diagnostical tool in patient with chronic obstructive pulmonary disease (COPD). As shown in previous studies and pointed out by the Fleischner society, an additional scan in expiration reflects the pathophysiology of this complex disease better and extends the clinical information of the CT.

Nevertheless, this scan is leading to an increase in radiation dose. But currently it is unclear if this increased radiation dose is proportional to the additional clinical value when compared to inspiration-only protocols. Therefore, the aim of this study was to compare the organ specific radiation doses of a combined inspiration-expiration CT on a 3rd generation dual-source scanner with noncontrast-enhanced chest CTs of two clinical routine scanners. Therefore, the radiation doses of nearly 2000 chest CTs have been evaluated.

Registry
clinicaltrials.gov
Start Date
August 2014
End Date
September 2017
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Joshua Gawlitza

Head of COPD imaging research

Universitätsmedizin Mannheim

Eligibility Criteria

Inclusion Criteria

  • noncontrast-enhanced chest CT performed on one of the named devices
  • imaging performed between August 2014 and September 2017
  • CT protocol used as previously specified

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

organ specific radiation doses

Time Frame: The organ dose calculations have been performed retrospectively. Therefore, the time frame is variable. The time set for the final outcome calculations was September 2017. Therefore, the time frame varies between 3 years and 1 week.

Organ specific radiation doses of 17 individual organs

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