Comparison of blood levels and Sedation of Dexmedetomidine through mouth and nose in Childre

Not Applicable

Completed

• Conditions: Health Condition 1: H00-H59- Diseases of the eye and adnexa

• Registration Number: CTRI/2021/04/032511
• Lead Sponsor: I

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-08-19
• Last Update Posted: 6 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

1) ASA Grade 1 and 2 Patients.

2)Weight 10 to 30 kg.

Exclusion Criteria

1)Parental refusal

2)ASA III, IV

3)OSA

4)Difficult airway

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the pharmacokinetics of 2 mcg/kg sublingual and intranasal dexmedetomidine in childrenTimepoint: Forty-five minutes before the induction of anaesthesia up to 120 minutes after surgery.

Secondary Outcome Measures

Name	Time	Method
1)To evaluate the onset and duration of sedation with sublingual and intranasal Dexmedetomidine. <br/ ><br>2)To evaluate the quality of parental separation and the mask acceptance with sublingual and intranasal Dexmedetomidine <br/ ><br>3)To evaluate perioperative operative vitals (HR, SpO2, MAP) with sublingual and intranasal Dexmedetomidine <br/ ><br>4)To evaluate perioperative analgesia with sublingual ad intranasal Dexmedetomidine and post-operative recovery score with sublingual and intranasal DexmedetomidineTimepoint: Forty-five minutes before the induction of anaesthesia upto 120 minutes after surgery.