NL-OMON56592招募中不适用
Biomarker-Guided Intervention to Prevent Acute Kidney Injury after Major Surgery; The Prospective Multicenter Randomized Controlled Interventional Trial - BigpAK-2
niversity Hospital Muenster, Dept. of Anesthesiology, Intensive Care Medicine and Pain Therapy0 个研究点目标入组 30 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Patients after major surgery who need to be admitted to the ICU
- •2. Age > 18 years
- •3. [TIMP-2]*[IGFBP7] >= 0.3 4-18 hours after surgery
- •4. Inserted jugular central venous line and a urinary catheter
- •5. Written informed consent
- •6. At least one additional risk factor for AKI:
- •a. Age > 75 years
- •b. Critical illness such as ongoing requirement of vasopressors or mechanical
- •ventilation postoperatively
- •c. Pre- existing chronic kidney disease (eGFR< 60 ml/ min)
- •d. Intraoperative use of radio contrast agents.
排除标准
- •1. Pregnancy or breastfeeding
- •2. Pre- existing high stages of chronic kidney disease (>=stage 4 i.e. eGFR < 30
- •3. Kidney transplant within the last 12 months
- •4. Known (Glomerulo-) Nephritis, interstitial nephritis or vasculitis
- •5. Anuria at inclusion time
- •6. Preexisting AKI
- •7. Renal replacement therapy within the last 90 days
- •8. Indication for renal replacement at the time of inclusion
- •9. Participation in another interventional trial that investigates a
- •drug/intervention that affects
- •the kidney function
- •10. Persons held in an institution by legal or official order
- •11. Persons with any kind of dependency on the investigator or employed by the
- •responsible
- •institution or investigator
研究者
相似试验
已完成
不适用
Biomarker Guided Intervention for Prevention of Acute Kidney InjuryAcute Kidney InjuryNCT02500394University Hospital Regensburg135
已完成
4 期
Biomarker-based treatment option for preschool children with recurrent wheezeBronchial asthmaJPRN-UMIN000008335Mie National Hospital60
招募中
不适用
Validation of Biomarkers Performance to Reduce Antibiotics overUse in newBorns With Suspected Clinical Signs of InfectionSNeonatal Late Onset SepsisNCT06058819Hospices Civils de Lyon358
尚未招募
不适用
Biomarker based intervention strategies to combat adverse effects of shift workslaap, vermoeidheid, wellbevindenmetabolic healthsleep1000301810040991NL-OMON53661Erasmus MC, Universitair Medisch Centrum Rotterdam75
尚未招募
不适用
Detection of Diagnostic Biomarkers for Pediatric Rheumatic Diseases Using Proteomic AnalysisPediatric Rheumatic Diseases (juvenile idiopathic arthritis(JIA), systemic lupus erythematosus(SLE), juvenile dermatomyositis(JDM), Sjogren syndrome(SS),etc)JPRN-UMIN000021679Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University200