MedPath

Study on the relationship between Lymphocyte subsets, tumor Necrosis Factor-a and TCM Syndromes of Depressio

Phase 1
Recruiting
Conditions
depression
Registration Number
ITMCTR2200005617
Lead Sponsor
Zhejiang Litongde Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1) meet the diagnostic criteria of ICD-10 depressive episode; 2) 17 items of Hamilton Depression scale (Hamilton rating scale for depression, HAMD) score > 7; 3) 14-65 years old, regardless of sex, education, occupation, economic status, etc.; 4) No serious heart, liver and kidney diseases, no brain organic diseases, no tumors, blood history, rheumatism, malnutrition and nervous system degeneration. 5) did not take immunomodulator and hormone preparation for at least half a year, and did not take antipyretic and analgesic drugs within 2 weeks; 6) patients were unconscious and could understand the contents of the scale and cooperate with treatment. 7) obtain informed consent.

Exclusion Criteria

1) there are other mental disorders such as bipolar disorder, schizophrenia, or depressive episodes secondary to other mental or somatic diseases; 2) there are serious diseases such as heart, liver, kidney, blood, rheumatism, tumor, malnutrition and nervous system degeneration, there are brain organic diseases; 3) there is a history of abuse of tobacco, alcohol and other psychoactive substances. 4) taking immunomodulator and hormone preparation within half a year, taking antipyretic and analgesic drugs within 2 weeks, 5) patients with disturbance of consciousness and 6) no informed consent.

Study & Design

Study Type
Observational study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
TNF-a;Lymphocyte subsets;
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath