Etude de la Perception Auditive après Exposition PROgressive Aux Sons Aversifs Chez Des Personnes MISophonEs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Institut Pasteur
- Enrollment
- 110
- Locations
- 2
- Primary Endpoint
- score on a visual analogue scale from 0 (pleasant sound) to 10 (unpleasant sound)
Study Overview
Brief Summary
The primary objective of the project is to characterise and measure the auditory perception of subjects with misophonia compared with the auditory perception of control subjects.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •For all participants
- •Obtain oral consent from the participant after receiving information about the study,
- •Be 18 years or older on the day of inclusion,
- •Be fluent in French (spoken and written),
- •Have no known hearing loss, verified by pure tone audiometry.
- •Declare that they do not have tinnitus,
- •Declare that they do not have hyperacusis, verified by measuring discomfort thresholds.
- •Be affiliated to the social security or equivalent scheme.
- •For participants with misophonia:
- •Declare discomfort, reduced tolerance to specific sounds (mouth noises, throat clearing, breathing, etc.).
Exclusion Criteria
- •Bear the after-effects of an ear infection and/or have a history of an ENT disease that permanently affects hearing or balance (vestibular schwannoma, Ménière's disease, sudden or fluctuating deafness, congenital hypoacusis),
- •Be under guardianship,
- •deprived of liberty by judicial or administrative decision, or subject to legal protection.
Arms & Interventions
Control group
Intervention: Psychoacoustic test (Behavioral)
Control group
Intervention: semi-structured interviews (Other)
Misophonia group
Intervention: Psychoacoustic test (Behavioral)
Misophonia group
Intervention: semi-structured interviews (Other)
Misophonia group
Intervention: Exposure to unpleasant sounds (Other)
Outcomes
Primary Outcomes
score on a visual analogue scale from 0 (pleasant sound) to 10 (unpleasant sound)
Time Frame: 1 week after enrollment
sounds will be presented at different decibels and the subject will be asked to rate the pleasantness/unpleasantness of the sound on a visual analogue scale
score on a visual analogue scale from 0 (very low intensity) to 10 (extremely intense)
Time Frame: 1 week after enrollment
sounds will be presented at different decibels and the subject will be asked to rate the intensity of the sound on a visual analogue scale
Secondary Outcomes
- Measuring the consistency of the psychoacoustic test(1 week after enrollement)
- the number of redundant themes in the semi-structured interviews(1 month after enrollment)
- score on a visual analogue scale from 0 (very little discomfort) to 10 (extreme discomfort)(1 month after enrollment and 2 months after enrollment)