Ropivacaine After Sternotomy
- Registration Number
- NCT02449486
- Lead Sponsor
- Kuopio University Hospital
- Brief Summary
Continuous ropivacaine infusion to sternotomy wound after coronary artery bypass grafting (CABG) or heart valve surgery to diminish postoperative pain.
- Detailed Description
A multiporous catheter will be introduced into sternotomy wound to CABG or heart valve surgery patients and continuous ropivacaine infusion 4 ml/h will be started immediately after surgery. Ropivacaine infusion will be administered during 48 postoperative hours. All patients receive patient controlled analgesia (PCA) oxycodone after extubation in the PACU. All patients receive a standardized anesthesia during surgery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- Elective CABG or heart valve surgery patients
Exclusion Criteria
- Psychic disorders
- Sleep apnea syndrome
- Diabetes mellitus (insulin dependent)
- Obesity, body mass index (BMI) ≥ 35
- Cardiac insufficiency, ejection fraction (EF) ≤ 30
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Ropivacaine Ropivacaine Ropivacaine 4 ml/h (8 mg/h) continuous infusion for 48 hours Placebo Ropivacaine Saline infusion 4 ml/h for 48 hours
- Primary Outcome Measures
Name Time Method Postoperative oxycodone consumption 48 postoperative hours postoperative PCA administered oxycodone
- Secondary Outcome Measures
Name Time Method Pain measured with Visual Analog Scale 48 postoperative hours pain measured with VAS at rest and on movement
Trial Locations
- Locations (1)
Kuopio University hospital
🇫🇮Kuopio, Finland