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Clinical Trials/NCT07261813
NCT07261813
Not yet recruiting
Not Applicable

Chronic Obstructive Pulmonary Disease, Quality of Life, COPD Assessment Test, Nepal, Dyspnea, Spirometry

Institute of medicine, Maharagjung medical campus0 sites71 target enrollmentStarted: December 1, 2025Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Institute of medicine, Maharagjung medical campus
Enrollment
71
Primary Endpoint
Health-Related Quality of Life (HRQoL) Score (COPD Assessment Test - CAT)

Overview

Brief Summary

Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. The study "Quality of life among people living with Chronic Obstructive Pulmonary Disease- visiting spirometry center of Tribhuvan University Teaching Hospital, Kathmandu Nepal" aims to assess the quality of life (QOL) of COPD patients and the factors affecting it.

A cross sectional study will be performed among the patients visiting Spirometry center of Tribhuvan University Teaching Hospital, Kathmandu Nepal using Convenience Sampling. Ethical approval will be obtained from Institutional Review Board (IRB) of TUTH and written/verbal consent for data collection will be obtained from Teaching hospital authority as well as the respondents. CAT questionnaire will be used to assess quality of life and the Medical Research Council questionnaire will be used to assess the severity of dyspnea. Data management and analysis will be conducted through Statistical Package for Social Sciences (SPSS) version 26.0.

Study Design

Study Type
Observational
Observational Model
Other
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
20 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age ≥ 20 years
  • Referred to the spirometry center of Tribhuvan University Teaching Hospital
  • Confirmed diagnosis of COPD based on GOLD criteria: post-bronchodilator FEV1/FVC \< 0.7

Exclusion Criteria

  • Unable to perform acceptable spirometry maneuvers
  • Presence of significant respiratory diseases that can confound COPD assessment (e.g., asthma, bronchiectasis, active tuberculosis)

Outcomes

Primary Outcomes

Health-Related Quality of Life (HRQoL) Score (COPD Assessment Test - CAT)

Time Frame: 1 month

The COPD Assessment Test (CAT) score ranges from 0 to 40, with 0 indicating no impact and 40 indicating the worst impact on quality of life. Higher scores represent worse outcomes.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Institute of medicine, Maharagjung medical campus
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Abhishek Kumar Shah

Principal Investigator

Institute of medicine, Maharagjung medical campus

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