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Clinical Trials/NCT03748342
NCT03748342
Completed
Not Applicable

The Use of a Second-Generation Laryngeal Mask Airway Versus Endotracheal Tube in Obese Patients

University of Texas Southwestern Medical Center2 sites in 1 country97 target enrollmentJune 27, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obese
Sponsor
University of Texas Southwestern Medical Center
Enrollment
97
Locations
2
Primary Endpoint
Proportion of Participants With Postoperative Hypoxia
Status
Completed
Last Updated
last year

Overview

Brief Summary

This prospective, randomized, comparative study is intended to enroll a total of 148 patients with a BMI 30-49.9 kg/m2 undergoing surgery at Parkland Hospital. The efficacy and performance of a second-generation LMA will be compared to endotracheal intubation. A standardized anesthetic protocol that is usual and customary for the type of operation the patient is having will be provided to the anesthesia teams of enrolled subjects. The remainder of the anesthetic care of the subject will not deviate from the standard of care.

Registry
clinicaltrials.gov
Start Date
June 27, 2019
End Date
February 3, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tiffany B Moon

Associate Professor

University of Texas Southwestern Medical Center

Eligibility Criteria

Inclusion Criteria

  • 18-80 years old
  • Obese (BMI \> or equal to 30 kg/m2
  • Scheduled for a non-emergent surgery that requires general anesthesia (e.g., orthopedic, breast, urological, colorectal, ENT, vascular, general surgery)
  • Willing and able to consent in English or Spanish
  • No current history of advanced pulmonary or cardiac disease

Exclusion Criteria

  • Age less than 18 or older than 80
  • BMI ≥50 or \< 30 kg/m2
  • Patient does not speak English or Spanish
  • Expected surgical duration longer than 4 hours
  • Planned postoperative ICU admission
  • Patient refusal
  • Monitored anesthesia care (MAC) or regional anesthesia planned
  • Pregnant or nursing women
  • "Stat" (emergent) cases
  • Known or suspected difficult airway

Outcomes

Primary Outcomes

Proportion of Participants With Postoperative Hypoxia

Time Frame: Up to 80 minutes post-operatively

Patients in the 2 groups will be assessed for postoperative hypoxia (1 or more episodes) in the PACU using a visual analog scale.

Secondary Outcomes

  • Alterations in Blood Pressure(Intra-operatively)
  • Alterations in Heart Rate(Intra-operatively)
  • Alterations in Oxygen Saturation (at Baseline)(Baseline)
  • Alterations in Oxygen Saturation (at T15)(at 15 mins postoperatively)
  • Alterations in Oxygen Saturation (at T45)(at 45 mins postoperatively)
  • Alterations in Oxygen Saturation (at T80)(at 80 mins postoperatively)
  • Alterations in Respiratory Rate(Baseline)

Study Sites (2)

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