Investigating the reliability and validity of clinical and instrumental assessments of xerosis cutis in the context of vulnerable stages of life: a descriptive study

Recruiting

• Conditions: L85.3; Xerosis cutis

• Registration Number: DRKS00033630
• Lead Sponsor: Charité Universitätsmedizin Berlin, Abteilung für Dermatologie, Venerologie und Allergologie, Clinical Research Center for Hair and Skin Science and the Institute of Clinical Nursing Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-06-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

o Predisposition to dry skin
o At least 50% of participants must exhibit clinically visible scaling on arms and legs
o Written, informal consent, provided in person (the participant must be able to communicate)
o Willingness and ability to fulfill the requirements of the study

Vulnerable phases refer to the following circumstances:

Progressive frailty (from the age of 70) requires considerable psychological adjustments. This phase is characterized by increasing physical weakness and an increased risk of falls and injuries. With age, chronic illnesses such as osteoporosis and cardiovascular disease become more frequent, affecting physical fitness and mobility.

Women aged around 40 in particular go through hormonal changes due to the menopause, which bring hot flushes, mood swings and other symptoms. These changes mark the end of the reproductive years and require adjustments to the new physical and emotional realities.

Exclusion Criteria

o Participants diagnosed with active atopic dermatitis or other inflammatory chronic skin conditions / severe dermatological disorders at the discretion of the investigator
o Subjects, who are unable to understand the subject’s information, e.g. for linguistic or psychiatric reasons, and to give their consent
o Subjects, who have forfeited their freedom by administrative or legal decision or under guardianship o Subjects currently participating in or in the exclusion period of another study

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The study is based on an exploratory descriptive design and no primary endpoints are defined.

Secondary Outcome Measures

Name	Time	Method
The study is based on an exploratory descriptive design and no secondary endpoints are defined.