Repetitive Transcranial Magnetic Stimulation

Not Applicable

Completed

• Conditions: Schizophrenia

• Registration Number: NCT00169689
• Lead Sponsor: Heinrich-Heine University, Duesseldorf

Brief Summary

The study is a prospective, randomized, double-blind sham-controlled study.

Detailed Description

The principal objective of this trial is to investigate the effect of left prefrontal high frequency rTMS on negative symptoms in schizophrenia.

Study Timeline

• Study Start: 2003-06
• Study First Submitted: 2005-09-09
• Study First Submitted QC: 2005-09-09
• Study First Posted: 2005-09-15
• Study Completion: 2007-08
• Status Verified: 2008-01
• Last Update Submitted: 2008-01-28
• Last Update Posted: 2008-01-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• DSM-IV criteria for schizophrenia
• age between 18 and 60
• informed consent
• right handed patient
• no change of antipsychotic treatment > 2 weeks before recruitment

Exclusion Criteria

• seizures, epilepsy
• history of severe head injury
• status post implantation of a cardiac pacemaker or other electronic devi-ses

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Clinical Global Impression;	November 2007

Secondary Outcome Measures

Name	Time	Method
Global psychosocial functioning (GAF), PANSS-Negative Subscale,changes in EEG, heart rate variability, cortisol daytime profile, catecholamines, cognitive functioning	November 2007

Trial Locations

Locations (1)

Joachim Cordes; 🇩🇪 Düsseldorf, Rhineland, Germany