Repetitive Transcranial Magnetic Stimulation
Not Applicable
Completed
- Conditions
- Schizophrenia
- Interventions
- Procedure: rTMS, "repetitive transcranial magnetic stimulation"Other: rTMS
- Registration Number
- NCT00169689
- Lead Sponsor
- Heinrich-Heine University, Duesseldorf
- Brief Summary
The study is a prospective, randomized, double-blind sham-controlled study.
- Detailed Description
The principal objective of this trial is to investigate the effect of left prefrontal high frequency rTMS on negative symptoms in schizophrenia.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- DSM-IV criteria for schizophrenia
- age between 18 and 60
- informed consent
- right handed patient
- no change of antipsychotic treatment > 2 weeks before recruitment
Exclusion Criteria
- seizures, epilepsy
- history of severe head injury
- status post implantation of a cardiac pacemaker or other electronic devi-ses
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description rTMS rTMS sham coil system versus verum rTMS stimulation rTMS rTMS, "repetitive transcranial magnetic stimulation" sham coil system versus verum rTMS stimulation
- Primary Outcome Measures
Name Time Method Clinical Global Impression; November 2007
- Secondary Outcome Measures
Name Time Method Global psychosocial functioning (GAF), PANSS-Negative Subscale,changes in EEG, heart rate variability, cortisol daytime profile, catecholamines, cognitive functioning November 2007
Trial Locations
- Locations (1)
Joachim Cordes
🇩🇪Düsseldorf, Rhineland, Germany