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Clinical Trials/NCT04084236
NCT04084236
Unknown
Not Applicable

The Effects of Transcutaneous Electrical Nerve Stimulation on People With Knee Osteoarthritis (OA) and or Chronic Pain

Omron Healthcare Co., Ltd.1 site in 1 country30 target enrollmentJuly 15, 2019
ConditionsKnee Pain

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Pain
Sponsor
Omron Healthcare Co., Ltd.
Enrollment
30
Locations
1
Primary Endpoint
6-minute walk test (6MWT)
Last Updated
6 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the effect of TENS at the knee pain.

Registry
clinicaltrials.gov
Start Date
July 15, 2019
End Date
May 30, 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Male or Female between the ages of 45 years or older
  • Ultrasonography scale of 0-3 for grading of primary Knee OA of the knee(s)
  • Pain perceived as a minimum of 3/10 on a 0-10 pain scale with 24 hours of the each visit
  • No phobia of electrical stimulation
  • No pain or anti-inflammatory medication will be taken during study
  • OA and or Chronic knee pain, Injury/pain that began minimum of 6- weeks before the beginning of the study.

Exclusion Criteria

  • Pregnancy
  • Diabetes Mellitus
  • Neuropathy
  • Uncontrolled HTN
  • Past surgery in the region to be treated by TENS or had received an intra-articular corticosteroid or hyaluronic acid injection within 6 months prior to enrollment
  • Arthritis (RA) in the area to be treated by TENS
  • Allergic to tape/electrodes
  • History of knee joint replacement or tibial osteotomy
  • Undergoing physical therapy
  • Any major joint pain (e.g., back, hip, or ankle) that could limit functional ability

Outcomes

Primary Outcomes

6-minute walk test (6MWT)

Time Frame: 2 hours

In the 6MWT, the participants will walk as far as they could within 6 minutes. They will not be allowed to carry a watch or provided feedback during the trial. Although rest periods are allowed, time recording will continue. The participants will be provided encouragement at 1-minute intervals.

stair climb test

Time Frame: 2 hours

An 11-step stairway with a step height of 17 cm will be used. Participants will begin with both feet on the bottom landing, then ascend and descend the stairway as fast as possible, and finally stop with both feet back on the bottom landing while using a handrail support, if required. Time recording will be started when the participant is signalled to start and ended when the participant returns with both feet on the ground.

The Knee injury and Osteoarthritis Outcome Score (KOOS)

Time Frame: 2 hours

The Knee injury and Osteoarthritis Outcome Score (KOOS) was developed as an extension of the WOMAC Osteoarthritis Index with the purpose of evaluating short-term and long-term symptoms and function in subjects with knee injury and osteoarthritis. The KOOS holds five separately scored subscales: Pain, other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related Quality of Life (QOL).

VAS(Visual Analog Scale score) for knee pain

Time Frame: 2 hours

The mean knee pain during the stair climb test, TUG test, and 6MWT will be measured using the VAS. Participants will record their level of knee pain by drawing a vertical mark between the ends of a 10-cm horizontal line. The 0-cm end and the 10-cm end represented no pain and the most extreme pain, respectively.

The Hospital Anxiety and Depression Scale (HADS)

Time Frame: 2 hours

HADS was found to perform well in assessing the symptom severity of anxiety disorders and depression in in the general population. The sensitivity and specificity for both HADS-A and HADS-D of approximately 0.80. The questionnaire comprises seven questions for anxiety and seven questions for depression.

Perceived Competence Scale (PCS) questionnaire

Time Frame: 2 hours

The Perceived Competence Scale (PCS) concerns feelings about behaving in healthy ways. This is a short 4-item questionnaire that assesses the degree to which participants feel confident about being able to make (or maintain) a change toward a healthy behavior, participate in a health-care program, or carry out a treatment regimen/physical tests.

timed Up and Go test (TUG)

Time Frame: 2 hours

The participant will sit down at first and then stand up when given the signal to start. As fast as possible, the participant will walk 3 meters toward a cone on the floor, circle it, walk back 3 more meters toward a chair, and finally sat down. Timing begins on the signal to start and ends when the participant completely sits down with their back resting on the backrest of the chair.

Secondary Outcomes

  • 2-step test(2 hours)
  • stand-up test(2 hours)
  • Knee extensor strength(2 hours)

Study Sites (1)

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