Strategies for Assessment of Fluid Overload in Acute Decompensated Heart Failure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Failure
- Sponsor
- Region Skane
- Enrollment
- 21
- Locations
- 2
- Primary Endpoint
- Rehospitalization/mortality
- Status
- Terminated
- Last Updated
- 2 years ago
Overview
Brief Summary
Heart failure (HF) is the endstage of all heart disease, characterized by inability of either the left or right heart or both to maintain sufficient output of blood for the demands of the body at normal filling pressures. Patients with HF are often admitted to hospital with decompensation and treated with diuretics. Residual congestion at discharge is associated with increased risk of early rehospitalization and adverse outcomes. However, determination of residual decompensation is complicated and a large number of patients admitted with decompensated heart failure are likely discharged before optimal decongestion has been achieved. Lung ultrasound (LUS) is a promising method to determine residual decompensation with the evaluation of B-lines. In this study our primary aim is to evaluate if LUS together with echocardiographic evaluation of filling pressure according to the European Society of Cardiology (ESC) algorithm performs better than clinical assessment to determine fluid status and risk of early rehospitalization in patients hospitalized for AHF.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Acute coronary syndrome, cardiogenic chock
Outcomes
Primary Outcomes
Rehospitalization/mortality
Time Frame: 2021-2023
Rehospitalization or death within 30 days due to decompensated heart failure