NCT04679285已完成不适用
Pilot Study to Assess Minimal Residual Disease on Cryopreserved Ovarian Fragments in Younger Patients Treated for Acute Myeloid Leukemia
University Hospital, Lille1 个研究点 分布在 1 个国家目标入组 9 人开始时间: 2021年4月26日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- Percentage of patients without detectable MRD in ovarian tissue
研究概览
简要总结
Cryopreservation of ovarian cortex represents an option for fertility preservation in patients diagnosed with acute myeloid leukemia and requiring allogeneic stem cell transplantation.
This pilot study aims to evaluate the minimal residual disease on ovarian fragments harvested before allogeneic stem cell transplantation at the time of complete remission.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 2 Years 至 40 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patient diagnosed with AML
- •At least one molecular marker identified at AML diagnosis
- •Patients who undergo ovarian tissue cryopreservation for fertility preservation in complete remission, before hematopoietic stem cell transplantation.
排除标准
- •Other diagnostic
- •No marker available at AML diagnosis
- •No bone marrow/ovarian fragment available at the time of complete remission
结局指标
主要结局
Percentage of patients without detectable MRD in ovarian tissue
时间窗: Up to 6 months
次要结局
- Percentage of patients with MRD detected in ovarian tissue and bone marrow.(Up to 1 month)
研究者
研究点 (1)
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