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临床试验/NL-OMON50647
NL-OMON50647已完成不适用

The effects of citrus extract administration on gastrointestinal health - The effects of citrus extract on gastrointestinal health

niversiteit Maastricht0 个研究点目标入组 128 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
128

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • Patients with IBS, Calprotectin levels 15-150 µg/g feces, Age 18-70 years, BMI
  • < 35 kg/m2

排除标准

  • * Comorbidities that may influence gut microbiota composition or which might
  • limit participation in or completion of the study protocol (to be decided by
  • the principle investigator)
  • * Abdominal surgery interfering with gastrointestinal function (to be decided
  • by the principle investigator)
  • * Use of immunosuppressive drugs within 3 months before study period
  • * Use of other medication interfering with endpoints
  • * Changes in medication that may significantly affect the study outcome
  • according to the investigator*s judgment within 1 month prior to the study
  • * Changes in clinical activity scores within 3 weeks prior to the study
  • * Administration of investigational drugs or participation in any scientific
  • intervention study which may interfere with this study (to be decided by the
  • principle investigator) in the 180 days prior to the study
  • * Use of dietary supplements containing antioxidants, minerals and vitamins
  • * Excessive intake of foods with a high polyphenol concentration
  • * Use of antibiotics within 3 months prior to the start of study
  • * Use of pre-or probiotics within 1 month prior to the study
  • * Use of oral corticosteroids within 1 month prior to the study
  • * Blood donation within 1 month prior to the study
  • * Known pregnancy or lactation.
  • * Excessive drinking (>20 alcoholic consumptions per week)
  • * History of any side effects towards the intake of flavonoids or citrus fruits

研究者

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