A Comparative Clinical Study to Evaluate The Efficacy Of Gud Haritaki and Dravyadi Leha In The Management Of Pandu Roga with special reference To Iron Deficiency Anaemia Amomg Children.

Pandu is a disease characterized by pallor of body which strikingly resembles with "Anaemia’ of modern science. Iron deficiency anaemia (IDA) is a very common nutritional disorder worldwide and is known to affect approximately one third of the global population. While its incidence in affluent countries is low, the incidence of IDA in India is very high. According to National Family Health Survey (NFHS) III data, the incidence of anemia in urban children is 71%, rural is 84%, and overall is 79%. It occurs when there is a decrease in total iron body content, severe enough to diminish erythropoiesis and cause anaemia. Rakta has been considered as a key factor for the Jeevana, Prinana, Dharana and Poshana karma of the body. Many a times it is seen that Rakta gets vitiated by Doshas, mainly by Pitta dosha as Rakta is Pittavargiya and disease like Pandu appear. In Ayurveda, Pandu is considered as a specific disease with its own pathogenesis and treatment. Thus an attempt has been made to study disease Pandu Roga according to Ayurvedic text in the parlance of Iron Deficiency Anaemia. In modern medicine, there is good treatment for Anaemia with considerable result but that is only for acute deficiencies Anaemia. No significant therapy is there for Chronic Anaemia which occur due to metabolic defects. Ayurveda can provide better management in this area. Iron deficiency anaemia is the most common type of anaemia throughout the world, although it occurs to a lesser extent in the United States because of the higher consumption of iron-rich red meat and the practice of food fortification (addition of iron to foods by manufacturers). In developing countries in tropical climates, the most common cause of iron deficiency anemia is infestation with worm.

Guda Haritaki yoga is one of the important medicines used in Panduroga mentioned in Bhaisajya Ratnavali. The primary etiological factor for Panduroga is Mandagni. With the aid of Haritaki’s deepana and pachana qualities, it can be cured. Pandu roga mostly contains vitiated rasa and rakta dhatu. Haritaki, a Rasayana medication, aids in restoring balance to vitiated Dhatu and encouraging the manufacture of healthy Dhatu. According to modern science Haritaki has antibacterial, anthelminthics, antioxidant, and immunomodulatory effects. Minerals like Iron and calcium are prevalent in jaggery (Gud), a sugarcane product. Jaggery contains 10-13 mg of iron per 100 g. Darvyadi Leha is a classical Ayurveda herbomineral formulation for Pandu Roga (anemia) described in Charak Samhita. Most of the ingredients of Darvyadi Leha possess qualities like Tridoshahara, Deepana, Pachana, Hridya, Yakriduttejaka, Krimighna, Shwasahara, Raktavardhaka and Rasayana. Both the drugs will help in managing pandu roga very well that’s why the present study entitled "A comparative clinical study to evaluate the efficacy of Gud haritaki & Darvyadi leha in the management of pandu roga W.S.R Iron deficiency anemia among children.