A Collaborative approach to Optimise MEdication use for Older people in Nursing homes (the COME-ON study): a cluster controlled trial

KU Leuven0 个研究点目标入组 1,804 人开始时间: 2015年11月18日最近更新: 2024年1月22日

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2016 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/26968520 protocol 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31402136 results (added 14/08/2019) 2019 Other publications in https://www.ncbi.nlm.nih.gov/pubmed/31829252 process evaluation (added 13/12/2019) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/36633299/ Drug–drug interaction results (added 09/01/2024)

•1. Participating nursing homes:
•The National Institute for Health and Disability Insurance (NIHDI) of Belgium launched a call in July 2013 to all Belgian nursing homes to apply for participation to the Come-On study. In total, 72 nursing homes were considered as eligible candidates. After the exclusion of duplicates (in case of the same coordinating physician, the same pharmacist or the same board of directions), 63 submission files were restrained.
•In agreement with NIHDI we decided to use the resulting 63 files to generate an intervention group of 30 NHs (as stipulated in the call launched by NIHDI in July 2013) and a control group of 33 NHs.
•Because of political reasons, it was decided on beforehand that each ‘entity’ in Belgium (12 in total: five Flemish provinces, five Walloon provinces, German-speaking community and Brussels-Capital Region) would have at least one NH in the intervention group.
•The number of NHs to be selected from each of the eight remaining entities was calculated on the number of inhabitants. We further stratified, within these entities, for experience with case conferencing and type of delivering pharmacy (hospital pharmacy versus community pharmacy). This resulted in 17 groups.
•Randomization within the groups was performed with SPSS.
•2. Participating nursing home residents:
•2.1. Resident of participating nursing home
•2.2. Participating GP
•2.3. 65 years and older
•2.4. A signed informed consent

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