Investigating the effects of zinc supplementation in patients with blood infectio

Phase 2

Conditions: sepsis.
Sepsis, unspecified organism
A41.9

Registration Number: IRCT20220208053971N3

Lead Sponsor: Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 56

Inclusion Criteria

Age over 18 years
patient admitted to the intensive care unit
patient with sepsis
Patients under enteral nutrition (nasal, mouth, stomach)

Exclusion Criteria

Pregnancy or breastfeeding
Body mass index over 35 (severe obesity)
Human immunodeficiency virus (HIV) disease
Patients at the time of transplantation
Patients with orders not to receive any type of enteral nutrition
Patients participating in other studies

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sequential Organ Failure Assessment. Timepoint: The effect of zinc supplementation on the SOFA score at the beginning of the study (before the intervention) and 1 week after the intervention in patients with sepsis in the intensive care unit. Method of measurement: SOFA questionnaire score.

Secondary Outcome Measures

Name	Time	Method
28-day mortality. Timepoint: The effect of zinc supplementation on the 28-day mortality at the beginning of the study (before the intervention) and 1 week after the intervention in patients with sepsis in the intensive care unit. Method of measurement: questionnaire.;Inflammatory factors. Timepoint: The effect of zinc supplementation on the Inflammatory factors at the beginning of the study (before the intervention) and 1 week after the intervention in patients with sepsis in the intensive care unit. Method of measurement: blood test.;Nutritional status. Timepoint: The effect of zinc supplementation on the nutritional status at the beginning of the study (before the intervention) and 1 week after the intervention in patients with sepsis in the intensive care unit. Method of measurement: mNUTRIC questionnaire score.