NCT00355992终止不适用
The Ischemia Modified Albumin In Diagnosing Ischemic New Events (IMAGINE Study).
Inverness Medical Innovations5 个研究点 分布在 2 个国家目标入组 1,250 人开始时间: 2006年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 1,250
- 试验地点
- 5
研究概览
简要总结
The purpose of the study is to evaluate the utility of Ischemia Modified Albumin (IMA) for risk stratification in patients presenting with chest discomfort and possible ischemic heart disease, and to evaluate the diagnostic and prognostic implication for IMA for major adverse cardiac events.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with primary complaints of chest discomfort or patients with symptoms indicative of a moderate to high probability for unstable angina clinically indicated reason for evaluation for ACS in the Emergency Department meeting tyhe following inclusion criteria will be enrolled:
- •Age >=21 years
- •Presentation within two hours of relief of most recent episode of chest pain or presence of on-going symptoms suggestive of coronary ischemia, which should be at least 10 minutes in duration.
- •Patients being evaluated for suspected ischemic signs and or symptoms (chest pain) at the time of presentation according to routine standard of care institutional chest pain protocol/pathway.
排除标准
- •Administration of thrombolytic medication prior to first (presentation) blood draw
- •Acute coronary syndrome (ACS) secondary to supply/demand inequity (i.e. known anemia, tachycardia, - defined as HR greater than 150 bpm, known sepsis, hypotension, defined as blood pressure < 90 mmHg).
- •Established diagnosis of liver cirrhosis
- •Other acute ischemic sources (ongoing severe claudication, mesenteric ischemia, acute TIA/CVA)
- •Renal failure requiring dialysis
- •Greater than 2 hours from relief of the most recent episode of chest pain or signs and symptoms suggestive of coronary ischemia.
- •Chest pain following traumatic injury to the chest
- •Evidence for sever systemic infection, manifesting as fever (temperature >100 degrees) and systolic blood pressure <100 mmHg
- •Patients unwilling or unable to provide written consent, without available next of kin
- •Cocaine-related chest pain
- •Pregnancy
- •Known diagnosis of active malignancy
- •Acute Bowel Ischemia
- •Severe peripheral vascular disease
- •Acute brain ischemia
研究者
研究点 (5)
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