Comparison of two different surgical techniques for the treatment of recurrent atrial fibrillation after initial catheter ablation.

Not Applicable

• Conditions: Atrial Fibrillation; Cardiovascular - Other cardiovascular diseases; Surgery - Surgical techniques

• Registration Number: ACTRN12624000676516
• Lead Sponsor: Alfred Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-28
• Last Update Posted: 3 June 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 264

Inclusion Criteria

1.Patients aged greater than 18 years old
2.Patients undergoing a second-time ablation procedure for AF
3.Durable PVI found on second procedure.
4.Persistent or paroxysmal AF - defined as a sustained episode lasting at least 7 days and less than three years (including or required chemical or electrical direct current cardioversion greater than 7 days post procedure)
5.At least one episode of recurrent AF must have been documented by electrocardiogram (ECG), holter, loop recorder, telemetry, trans telephonic monitoring (TTM), or implantable device within last 6 months of enrolment in this investigation
6.Patients must be able and willing to provide written informed consent to participate in this investigation; and
7.Patients must be willing and able to comply with all peri-ablation and follow- up requirements.

Exclusion Criteria

1.Patients with long-standing persistent AF - defined as a sustained episode lasting more than 3 years
2.Patients for whom cardioversion or sinus rhythm will never be attempted/pursued
3.Patients with AF felt to be secondary to an obvious reversible cause
4.Patients with contraindications to systemic anticoagulation with heparin or coumadin or a direct thrombin inhibitor
5.Pregnancy - will be assessed by patients informing the physicians
6.End stage renal or hepatic failure.
7.Severe valvular heart disease or cyanotic congenital heart disease.
8.Diagnosis of hypertrophic cardiomyopathy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified