JPRN-UMIN000002961已完成未知
Prospective, randomized, open-label, clinical trial comparing the effects of losartan (regular dose) /hydrochlorothiazide combination and losartan alone (high-dose) on blood pressure, endothelial function and markers for obesity/oxidative stress/chronic kidney diseases - Prospective, randomized, open-label, clinical trial comparing the effects of losartan/hydrochlorothiazide combination and losartan alone
ational Defense Medical College0 个研究点目标入组 30 人开始时间: 2010年1月3日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 80years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1)Allergy against losartan/hydrochlorothiazide 2)Poor-controlled hypertension (DBP>110 mmHg) 3)Poor-controlled diabetes (HbA1c>8.0 %) 4)Secondary hypertension 5)History of stroke, acute coronary syndrome or any cardiovascular diseases needed for inpatient-treatments within 6 months 6)Either level of aspartate aminotransaminase or alanine aminotransferase exceeds three-fold of the normal limits. 7)End stage renal disease 8)Symptomatic (NYHA III or IV) congestive heart failure 9)Malignancies or other diseases with poor prognosis 10)Pregnant 11)Subjects whose doctor in charge do not agree to join the trial
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