Minimally Invasive Versus Open Surgery for Perihilar Cholangiocarcinoma(PHC)：A Multicenter Real-world Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 783
- 试验地点
- 1
- 主要终点
- Postoperative length of stay
研究概览
简要总结
Brief Summary: This is a multicentric, retrospective, real-world study to investigate the surgical outcomes of minimally invasive surgery compared with open surgery for Perihilar Cholangiocarcinoma (PHC), with the perioperative characteristics and long-term overall survival being compared. We aimed to find out whether the minimally invasive surgery is safe or feasible for PHC. And we also want to find out patients with what kind of characteristic can be benefit from the minimally invasive surgery compared with the open approach.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically confirmed PHC.
排除标准
- •Peritoneal seeding or metastasis to the liver, para-aortic lymph nodes, or distant sites;
- •Non-adenocarcinoma histology;
- •Incomplete clinical data.
结局指标
主要结局
Postoperative length of stay
时间窗: up to 90 days
defined as the time from being admitted to hospital to discharge
Overall survival
时间窗: through study completion, an average of 5 year
defined as the duration from the first day after surgery to either the date of death or the last follow-up
次要结局
- Operation time(intraoperative)
- Mortality(up to 90 days)
- Operative details(intraoperative)
- Intraoperative blood loss(intraoperative)
- postoperative complications(up to 90 days)
- Reoperation within 90 days(up to 90 days)
- Readmission within 90 days(up to 90 days)
- Vessel reconstruction(intraoperative)
- R0 resection(intraoperative)
研究者
Renyi Qin
Professor
Tongji Hospital