Minimally Invasive Versus Open Surgery for Perihilar Cholangiocarcinoma(PHC)：A Multicenter Real-world Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Perihilar Cholangiocarcinoma
- Sponsor
- Renyi Qin
- Enrollment
- 783
- Locations
- 1
- Primary Endpoint
- Postoperative length of stay
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Brief Summary: This is a multicentric, retrospective, real-world study to investigate the surgical outcomes of minimally invasive surgery compared with open surgery for Perihilar Cholangiocarcinoma (PHC), with the perioperative characteristics and long-term overall survival being compared. We aimed to find out whether the minimally invasive surgery is safe or feasible for PHC. And we also want to find out patients with what kind of characteristic can be benefit from the minimally invasive surgery compared with the open approach.
Investigators
Renyi Qin
Professor
Tongji Hospital
Eligibility Criteria
Inclusion Criteria
- •Histologically confirmed PHC.
Exclusion Criteria
- •Peritoneal seeding or metastasis to the liver, para-aortic lymph nodes, or distant sites;
- •Non-adenocarcinoma histology;
- •Incomplete clinical data.
Outcomes
Primary Outcomes
Postoperative length of stay
Time Frame: up to 90 days
defined as the time from being admitted to hospital to discharge
Overall survival
Time Frame: through study completion, an average of 5 year
defined as the duration from the first day after surgery to either the date of death or the last follow-up
Secondary Outcomes
- Operation time(intraoperative)
- Mortality(up to 90 days)
- Operative details(intraoperative)
- Intraoperative blood loss(intraoperative)
- postoperative complications(up to 90 days)
- Reoperation within 90 days(up to 90 days)
- Readmission within 90 days(up to 90 days)
- Vessel reconstruction(intraoperative)
- R0 resection(intraoperative)