Effects of Allergic Rhinitis on the Nasal/Sinus Microbiome
- Conditions
- Allergic Rhinitis
- Interventions
- Other: Swab of vestibule and middle meatus of nose
- Registration Number
- NCT01461200
- Lead Sponsor
- University of Chicago
- Brief Summary
The purpose of this study is to find out if the bacteria present in the nose or sinuses of people with seasonal allergies changes during their allergy season. Another purpose of this study is to see if the bacteria present in the nose and sinuses of non-allergic people are the same as allergic people before the allergy season and if it changes during the season. Many bacteria are difficult to grow in the laboratory so the investigators are using analysis of DNA (the genetic material in cells) of the bacteria in the nose and sinus to find them. The investigators will be testing DNA of the bacteria only and not of the human subjects taking part in this study. This research is being done to help us understand how allergy affects bacteria in the nose and sinuses.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description allergics Swab of vestibule and middle meatus of nose - Non allergics Swab of vestibule and middle meatus of nose -
- Primary Outcome Measures
Name Time Method Change in bacterial profile of the sinuses Measured at baseline and 1 to 3 months later. DNA isolation to determine the bacterial profiles of samples taken at baseline (out of subjects' allergy season) and 1 to 3 months later during subjects' allergy season.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Chicago
🇺🇸Chicago, Illinois, United States