A study to compare effectiveness amongst two drugs ,one is injection desferoxamine with tablet deferasirox as a chelator in thalassemia patients
Phase 4
- Conditions
- Health Condition 1: null- THALASEMIA PATIENTS OF AGE GROUP 3 YEAR TO 18 YEARS
- Registration Number
- CTRI/2017/08/009441
- Lead Sponsor
- Dr Ratna D Bhojak
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Thalassemia major Patients
2 Pediatric age group 3 years to 18 years 3 On regular Deferasirox Therapy
4 Serum ferritin more than 1000mg/dl
5 With positive consent for study
Exclusion Criteria
1 Pt <3years
2 Pt > 18years
3 Patient with negative consent
4 Renal failure
5 Cataract
6 Ototoxicity
HIV positive
Hepatitis B positive
Av block
Asthma
On going infection( temporary exclusion included on recovery)
Severe allergy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To measure consecutive serum ferritin level in Participant with β Thalassemia major every 2 month with ongoing dosage of iron chelators ,admitted in Paediatric ward sir T hospital BhavnagarTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method THE VELOCITY IN DECREASING SERUM FERRITIN IN INJECTION CHELATOR IS BETTER THAN ORAL FORMTimepoint: 6 MONTHS