Efficacy of tolvaptan in transurethral resection of prostate
Not Applicable
Completed
- Conditions
- Benign prostatic hypertrophy
- Registration Number
- JPRN-jRCT1091220168
- Lead Sponsor
- Osaka Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 90
Inclusion Criteria
1) Benign prostatic hypertrophy
2) male: 20-89 year-old
3) patients showed consent of this study
Exclusion Criteria
1)emergency operation
2)simultaneously having different operation
3)serum sodium level <125mmol/l
4)having severe coronary diseases and cerebral vessel diseases
5)having severe liver dysfunctions
6)hyperkalemia
7)hemodialysis
8)permanent pacemaker
9)medication of CYP3A4 inhibitors
10)medication of vasopression related drugs
11)medication of inotropic agents
12)medication of Potassium-sparing diuretics
13)BMI>=35
14)Coagulation disorder
15)Severe complication with a diagnosis of 6 month remaining
16)Participation in other intervention studies
17)being judged as not appropriate for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of serum sodoum and occurrence of TUR syndrome
- Secondary Outcome Measures
Name Time Method 1) perioperative mortality<br>2) neurological and circulatory abnormality<br>3) serum creatinine levels<br>4) lactate levels