Feasibility and Prognosis of Early Rehabilitation in Patients With ECMO
- Conditions
- Extracorporeal Membrane Oxygenation
- Interventions
- Behavioral: rehabilation therapy
- Registration Number
- NCT05083624
- Lead Sponsor
- JinyanXing
- Brief Summary
ECMO is increasingly used in critically ill patients with severe circulatory and/or respiratory failure. Because of the catheterization of the femoral artery and femoral vein, usage of sedatives, and occasionally with neuromuscular blockers, ECMO patients are generally considered unsuitable for early activity. However, some recent retrospective studies and a small number of single-center, small-scale prospective studies have shown that early activity of ECMO patients is feasible, and early active activity is associated with recovery of independent function and reduction of delirium incidence.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
- ECMO time ≥1 day
- Aged older than16 years old and less than 70 years old
- coma deep
- sedation muscle relaxation (RAAS-3-5)
- Active bleeding deep vein thrombosis
- High dose of vasoactive drugs
- unstable vital signs
- Acute stage of myocardial infarction (within 2d)
- Malignant arrhythmia
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Rehabilitation group rehabilation therapy -
- Primary Outcome Measures
Name Time Method muscle ultrasound 7 days The thickness of intercostal muscle and rectus femoris muscle was measured by ultrasound
- Secondary Outcome Measures
Name Time Method ECMO duration time 30 days
Trial Locations
- Locations (1)
The Affiliated Hospital of Qingdao University
🇨🇳Qingdao, Shandong, China