An epigenetic analysis and gene expression profiling on autoimmune gastritis; a multicenter cross-sectional and prospective study

Not Applicable

Recruiting

• Conditions: autoimmune gastritis

• Registration Number: JPRN-UMIN000039528
• Lead Sponsor: Graduate School of Medicine, The University of Tokyo, Center for Epidemiology and Preventive Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-01
• Last Update Posted: 17 October 2023
• Study Completion: 2030-03-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

-Cases with medical history of H. pylori eradication treatment -Cases with regular use of proton pomp inhibitor (PPI) / potassium-competitive acid blocker (P- CAB) -Cases with medical history of surgical operation of the upper digestive tract -Cases with medical history of malignant disease (last 5 years, with the exception of intramucosal cancer cured by local treatment) -Patients with hereditary gastrointestinal tumor diseases (familial adenomatous polyposis, Lynch syndrome, hereditary nonpolyposis colorectal cancer, Peutz-Jeghers syndrome, Cowden syndrome, hereditary diffuse gastric cancer etc.) -Cases with use of 2 or more antiplatelet drugs or anticoagulants, or with coagulation abnormalities -Cases with regular use of steroids -Minor/elderly person/handicapped person who require special consideration

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Gene expression profiling and epigenetic analysis

Secondary Outcome Measures

Name	Time	Method
Statistical analysis associated with the risk of neoplasm emergence