Management of Obstructive Colon Tumors in Istanbul

• Conditions: Colon Cancer; Tumor Obstruction; Emergencies; Quality of Life

• Registration Number: NCT05424939
• Lead Sponsor: Istanbul Medipol University Hospital

Brief Summary

The aim of this study is to evaluate the outcome of obstructive colon cancer surgery in terms of days-to-starting adjuvant therapy and quality of life.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-05-11
• Status Verified: 2022-06
• Study Start: 2022-06-01
• Study First Submitted QC: 2022-06-17
• Last Update Submitted: 2022-06-17
• Study First Posted: 2022-06-21
• Last Update Posted: 2022-06-21
• Primary Completion: 2024-05-31
• Study Completion: 2024-05-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Acute intestinal obstruction due to colon cancer either preoperatively or intraoperatively detected
• Clinical findings of obstruction (Abdominal distention and pain, nausea or vomiting, and absence of bowel movements) confirmed by abdominal x-ray or CT

Exclusion Criteria

• Benign diseases
• Emergency surgery due to bleeding, perforation and other non-obstructive situations
• Recurrent colon tumors
• Rectal cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time-to-starting chemotherapy	1 year	Surgical procedures will be compared in terms of days-to-first chemotherapy

Secondary Outcome Measures

Name	Time	Method
Morbidity	3 months	90-day morbidity
Colorectal cancer-specific quality of life (EORTC QLQ - CR29) at 1 year	1 year	The European Organization for Research and Treatment of Cancer, Quality of Life Questionnaire-Colorectal Cancer (EORTC QLQ-CR29) scale will be recorded preoperatively and at 12 months. Surgical procedures will be compared in terms of improvement in EORTC QLQ-CR29 scores.
Mortality	3 months	90-day mortality

Trial Locations

Locations (2)

Medipol University Bahcelievler Hospital; 🇹🇷 Istanbul, Turkey

Medipol Mega Hospital; 🇹🇷 Istanbul, Turkey