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临床试验/IRCT20220508054780N4
IRCT20220508054780N4尚未招募1 期

A clinical trial to compare the effectiveness of agomelatine with placebo on rate of delirium in patients admitted to the cardiac surgery intensive care unit

Mashhad University of Medical Sciences0 个研究点目标入组 74 人开始时间: 待定最近更新:

试验速览

阶段
1 期
状态
尚未招募
入组人数
74

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 years 至 75 years(—)
性别
All

入选标准

  • Aged between 18 and 75 years
  • Staying more than 72 hours in the intensive care unit
  • Receiving medication following admission to hospital from the first day
  • Having stable hemodynamics based on confusion assessment method for the ICU (CAM-ICU)

排除标准

  • Patients who were treated with agomelatine before ICU admission
  • Having agomelatine allergies
  • Pregnant and breastfeeding women
  • Having Alzheimer
  • Having hepatic dysfunction
  • Having high APACHE II score
  • The patient dies in the first 3 days of admission
  • Patients who require of only parenteral nutrition
  • Using strong 1A2 inhibitors (ciprofloxacin, fluvoxamine)

研究者

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The effectiveness of agomelatine on rate of delirium | 临床试验