Open-label study to compare the bioavailability of an oral tablet of GLPG1972 relative to an oral solution after single-dose intake in healthy subjects and to evaluate the effect of food on the oral tablet.

Completed

Conditions: Arthritis.
10023213

Registration Number: NL-OMON42935

Lead Sponsor: Galapagos NV

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 12

Inclusion Criteria

healthy male subjects
18 - 50 years of age, inclusive
BMI 18.0 - 30.0 kilograms/meter2
Body weight at least 50 kilograms
non-smoking

Exclusion Criteria

Suffering from hepatitis B, hepatitis C, cancer or HIV/AIDS. In case of participation in another drug study within 8 weeks before the start of this study or being a blood donor within 12 weeks from the start of the study. In case of donating more than 1.5 liters of blood in the 10 months prior the start of this study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To compare the PK of an oral tablet of GLPG1972 with an oral solution of<br /><br>GLPG1972 under fasted conditions.<br /><br>To evaluate the effect of food (high-fat, high calorie meal) on the PK of<br /><br>GLPG1972 administered as an oral tablet.<br /><br>To evaluate the safety and tolerability of single oral doses of GLPG1972.</p><br>

Secondary Outcome Measures