Targeting Hypertension and Insulin Resistance With Heat Therapy
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Blood glucose
研究概览
简要总结
This is a clinical trial to determine if 30 sessions of far infrared sauna bathing can improve cardiovascular and metabolic function in adults with obesity.
详细描述
Obesity can increase the risk for cardiovascular and metabolic diseases. Lifestyle interventions are needed to reduce this risk. Far infrared saunas are one form of heat therapy that may help reduce these risks, however, there is limited research within a population with obesity. It is hypothesized that repeated far infrared sauna bathing will improve cardiovascular and metabolic function in adults with obesity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 59 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI between 30-45 kg/m2
排除标准
- •Diagnosed diabetes
- •Greater than stage 2 hypertension
- •Coagulopathies
- •Allergies to lidocaine
- •Medications affecting blood pressure
- •Blood clotting, and blood sugars
- •Desiring to become pregnant in the near future
- •Breastfeeding
- •BMI less than 30
- •BMI greater than 45 kg/m2
- •Exercising > 120 min/week
- •Taking medications (other than hormone contraceptives)
- •Not willing to stop taking medications (other than hormone contraceptives) for 24 hours before testing days
研究组 & 干预措施
Heat therapy
Group will undergo 30 sessions of heat therapy over approximately 10 weeks. Sessions will require participants to sit in a far infrared sauna for up to 45 min for 3 to 4 times per week.
干预措施: Heat therapy (Other)
Time control group
No participation in sauna bathing. Maintain lifestyle habits for approximately 10 weeks.
结局指标
主要结局
Blood glucose
时间窗: 10 weeks
Change in plasma glucose levels after Intervention
Blood pressure change
时间窗: 10 weeks
Change in systolic and diastolic blood pressures after 30 sessions of Intervention
次要结局
- Arterial stiffness reduction(10 weeks)
- Serum insulin(10 weeks)
研究者
Christopher T Minson, PhD
Professor
University of Oregon