Comparison of yoga vs usual care in Coronary Artery Disease Patients.

Not yet recruiting

Conditions: Old myocardial infarction,

Registration Number: CTRI/2023/05/052910

Lead Sponsor: Collaborative Centre for Research in Yoga and Naturopathy

Brief Summary: Background of the study:

Yoga has quickly risen to one of the most common complementary and alternative medicine practiced worldwide. Yoga has been used in the primary and secondary prevention of Cardiovascular disease(CVD) including Coronary artery disease(CAD). Many evidences suggest that yoga is safe and efficacious in reducing various risk factors of CAD such as stress, anxiety, depression, diabetes, obesity and hypertension. Yoga can be helpful in any form of preventive measure for CAD. If used as primordial preventive measure can lead to significant reduction in cardiovascular and many more non- communicable diseases.

Purpose of Trial:

Yoga has been associated with improvement in general health, cardiovascular risk prevention factors, and other NCDs. Yoga has shown improvement in BMI, Blood pressure, lipid profile, lesion progression in CAD. However, the biomolecules through which yoga acts on body is unclear in CAD. Thus this study investigates different risk factors of CAD. The study aims to investigate various immunological, inflammatory and neuropsychological markers of CAD patients. The study will aid in revealing the biomolecule that brings about the positive health effect in yoga practitioners. The study will generate evidence for the efficacy of Yoga protocol which is used in CAD care, later it will help in slowing down the progression of disease.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 150

Inclusion Criteria

1.Patients of 18 to 65 years who underwent PCI 2 -6 weeks prior to enrollment 2.Those who have LVEF of more than 40 % 3.Those who are not planned for revascularization during the study period 4.Those who have fair to good functional capacity.

Exclusion Criteria

1.Patients who are not willing to participate will be excluded, 2.Those who refractory or class III angina.
3.Those who have refractory or uncontrolled hypertension 4.Those who have physical disability and pregnant women 5.Life threatening arrhythmia 6.Obese persons and patients on hormonal therapy will be excluded 7.Any other significant chronic illness.
8.Those who are under other CR program.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare LVEF in two groups.	First 3 months and followup for next 3 months.
To compare inflammatory markers in two groups.	First 3 months and followup for next 3 months.
To compare effect on psychological issues.	First 3 months and followup for next 3 months.
To investigate effect of genetic polymorphism on outcome	First 3 months and followup for next 3 months.
To compare outcome on BMI, Lipid Profile.	First 3 months and followup for next 3 months.

Secondary Outcome Measures

Name	Time	Method
1.To compare changes in BMI andÂ Lipid Profile	2. To investigate the effect of genetic polymorphism

Trial Locations

Locations (1): Post Graduate Institute of Medical Education and Research, Chandigarh
🇮🇳
Chandigarh, CHANDIGARH, India
Post Graduate Institute of Medical Education and Research, Chandigarh
🇮🇳Chandigarh, CHANDIGARH, India
Dr Neelam Dahiya
Principal investigator
9876386810
drneelamdahiya@gmail.com