Does the use of a specific cognitive intervention for children with movement disorders improve functional outcomes following deep brain stimulation?

Not Applicable

Completed

• Conditions: Topic: Children, Neurological; Subtopic: Children (all Diagnoses), Neurological (all Subtopics); Disease: All Diseases, Neuro-muscular and Encephalitis; Nervous System Diseases; Hyperkinetic movement disorders

• Registration Number: ISRCTN57997252
• Lead Sponsor: King's College London (UK)

Brief Summary

2020 Other publications in https://pubmed.ncbi.nlm.nih.gov/33375553/ (added 25/04/2023) 2019 Other publications in https://pubmed.ncbi.nlm.nih.gov/30796136/ (added 25/04/2023) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33553070/ (added 25/04/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-03-09
• Study Completion: 2017-02-28
• Last Update Posted: 8 May 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Participants must express and evidence a willingness to participate
2. Sufficient receptive and expressive communication ability to follow simple instructions and engagement with treatment (including adequacy of English language)
3. Diagnosis of hyperkinetic movement disorder other than neurodegenerative conditions
4. Age 6-21 years
5. Manual Ability and Classification System (17) (MACS) levels IIII
6. Emerging skills in self-care such as starting to want to get undressed, brush own teeth, self-feed
7. Ability to mobilize independently
8. Requiring adult assistance to complete age appropriate activities. e.g. eating and drinking, toothbrushing, washing and dressing, making a sandwich, making a bed, etc
9. Cognitive ability of 6 years of age and IQ above 70 as assessed using the Wechsler Intelligence Scale for Children (WISC)
10. Deep Brain Stimulation in situ and without signs of infection

Exclusion Criteria

1. Pure spasticity or mixed phenotype when spasticity is dominant feature;
2. Dystonia arising due to a neurodegenerative condition
3. Scheduled for surgical treatment in the study period
4. Known signs of DBS infection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of functional performance for chosen goals is measured using the Performance Quality Rating Scale (PQRS) at baseline, post-intervention and 3 months follow up.