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Exercise, nutrition and muscle quality

Not Applicable
Conditions
Health Condition 1: E669- Obesity, unspecified
Registration Number
CTRI/2019/06/019941
Lead Sponsor
Submitted to ICMR
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Individuals between 30-60 years of age with BMI >=25 kg/m2, diagnosed to have sarcopenia based on the following definition of sarcopenia:

1 Appendicular skeletal muscle mass/height2: Men < 7.0 kg/m2, Women <6.0 kg/m2.

2 Hand grip strength Men: <27 kg Women: <16 kg

3 SPPB <=8 (The maximum score on the SPPB is 12)

4 4-minute gait speed < 0.8 m/s

Exclusion Criteria

1 Known or recently diagnosed diabetes mellitus or coronary heart disease

2 Contraindication to aerobic exercise or progressive resistance training

3 Any severe acute or chronic illness, severe end organ dysfunction, post organ transplant

4 Known malignancy, HIV/ HBsAg/Anti HCV positivity

5 Chronic alcohol use ( >30 g/day in men and >20 g/day in women) or any other drug abuse

6 Use of any medications that may affect the muscle function or mass such as corticosteroids, anabolic steroids, protein supplements, performance enhancing medications etc.

7 Pregnancy and lactation, any physical deformity or loss of extremity

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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