Pilot study of the feasibility of research on the application of bright light as a means of restoring the sleep-wake rhythm in patients with schizophrenia admitted to the locked ward, and by that means alleviating their psychotic symptoms.
Phase 2
Completed
- Conditions
- disturbed circadian rhythm in schizophrenia10039628
- Registration Number
- NL-OMON33052
- Lead Sponsor
- Parnassia (Den Haag)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
- All patients diagnosed with schizophrenia or schizoaffective disorder by a psychiatrist according to the DSM-IV TR classification.
- Patients who are admitted to the clinical institution KCVG.
- Patients for whom informed consent and informed consent by proxy has been given.
Exclusion Criteria
- Patients with diagnosis of bipolar disorder.
- Patients with a current manic episode measured with the Young Mania Rating Scale.
- Patients with contra-indications for light therapy after eye examination, such as glaucoma, retinopathy or cataracts.
- Patients with epilepsy in history or at present
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter is the change from baseline to endpoint in level of<br /><br>psychosis measured with the PANSS.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary study parameter is the change in the sleep-wake rhythm and<br /><br>activities measured with a sleep log and a social rhythm therapy scheme. </p><br>