Submacular Hemorrhage Associated With Retinal Arterial Macro Aneurysm

Not Applicable

Completed

• Conditions: Submacular Hemorrhage; Ruptured Retinal Arterial Macro Aneurysms
• Interventions: Procedure: Vitrectomy for submacular hemorrhage; Drug: subretinal injection of tissue-plasminogen activator

• Registration Number: NCT02120066
• Lead Sponsor: Kyorin University

Brief Summary

Evaluation of surgical outcome of vitrectomy with subretinal injection of recombinant tissue-plasminogen activator for submacular hemorrhage associated with retinal arterial macroanuerysms.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2013-06
• Status Verified: 2014-04
• Study Completion: 2014-04
• Study First Submitted: 2014-04-15
• Study First Submitted QC: 2014-04-18
• Last Update Submitted: 2014-04-18
• Study First Posted: 2014-04-22
• Last Update Posted: 2014-04-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• The patients with sub macular hemorrhage associated with ruptured retinal arterial macro aneurysms

Exclusion Criteria

• The eyes with preretinal or intraretinal hemorrhage at the fovea
• The patients with follow-up less than 3 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Vitrectomy	Vitrectomy for submacular hemorrhage	-
Vitrectomy	subretinal injection of tissue-plasminogen activator	-

Primary Outcome Measures

Name	Time	Method
Displacement of sub macular hemorrhage	one year	Anatomical recovery detected funduscopy and optical coherence tomography

Secondary Outcome Measures

Name	Time	Method
Visual acuity	one year	Visual recovery after surgery

Trial Locations

Locations (1)

Kyorin Eye Center; 🇯🇵 Mitaka, Tokyo, Japan