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STUDY OF SOME AYURVEDIC MEDICINES IN THE TREATMENT OF ASTHI KSHAYA(DECREASE OF BONE TISSUE)

Phase 3
Conditions
Health Condition 1: null- Patients of either sex with in the age group of 40-65 years of agecomplaining of Bone pain and decaying BMD score between -1 to -3 on DEXA scan selected for trial perticipent.
Registration Number
CTRI/2015/01/005474
Lead Sponsor
CENTRAL COUNCIL FOR RESEARCH IN AYURVEDIC SCIENCES
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
65
Inclusion Criteria

1Patients of either sex between 40 to 65 years of age.

2B.M.D -T. Score between ( -1 to -3 ) on DEXA Scan.

3Willing and able to participate for 14 weeks.

Exclusion Criteria

Exclusion Criteria

1.Patients who are consuming corticosteroids (more than 5mg/day of prednisolone or equivalent) for more than 3 months

2.Patients with history of Fragility Fracture.

3.Patients suffering from congenital disorders related to bone (Dysosteogenesis, Marfanâ??s Syndrome, etc.)

4.Patients with (Hypothyroidism and Hyperthyroidism, Hypoparathyroidism and Hyperparathyroidism, Cushingâ??s syndrome)

5.Patients with unstable CV diseases

6.Patients suffering from Osteomalacia.

7.Patients suffering from Malabsorption syndrome

8. Patients who have undergone Organ transplantation

9.Patients who are immobilized since > 6 weeks

10.Patients with history of bone fracture in last 6 months.

11.Patients with concurrent serious cardiac, Hepatic Dysfunction (defined as AST and/or ALT > 3 times of the upper normal limit) or Renal Dysfunction (defined as S. creatinine > 1.2mg/dl), uncontrolled Pulmonary Dysfunction (asthmatic and COPD patients) or other concurrent severe disease.

12.Patients with Diabetes Mellitus

13.Alcoholics and/or drug abusers.

14.Patients with evidence of malignancy

15.Patients suffering from major systemic illness necessitating long term drug treatment/Auto-Immune disorders (Rheumatoid arthritis, Psycho-Neuro-Endocrinal disorders, etc.)

16.Pregnant or lactating woman.

17.H/o hypersensitivity to any of the trial drugs or their ingredients

18.Patients who have completed participation in any other clinical trial during the past

Six (06) months.

19.Patients on calcium and Vitamin D supplementation.

20.Patients with history of Urolithiasis.

21.Known cases of Pagetâ??s disease of bone

22.Any other condition which the investigator thinks may jeopardize the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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