The effect of different exercise models on elderly people with knee osteoarthritis

Not Applicable

• Conditions: knee osteoarthritis; D018908; D018771

• Registration Number: RBR-2twzy65
• Lead Sponsor: niversidade São Judas

Brief Summary

Introduction: Osteoarthritis (OA) is a chronic multifactorial disease characterized by the gradual loss of cartilaginous tissue in synovial joints that causes pain and functional disability. Physical exercise has been proposed as a non-pharmacological strategy in the treatment of the disease, however, patients with OA are unable to perform exercises with high loads on the joint, which can increase the worsening of the disease. Therefore, the combination of different training strategies with low intensity associated with blood flow restriction (RFS) in patients with osteoarthritis may be an alternative form of exercise. However, these strategies have been little investigated. Objective: To investigate the effect of different exercise strategies with and without blood flow restriction on motor strength, muscle mass, functionality and pain perception in patients with knee osteoarthritis. Methodology: For this study, 60 patients of both sexes with a diagnosis of knee OA will be recruited. Patients will be randomly divided into four groups, namely: group 1 - control (CG), which will carry out only evaluations and tests; group 2 - physiotherapy (Fisio), which will be submitted to physiotherapy sessions with electrotherapy application, joint mobilization, dynamic strength training for hips, quadriceps, hamstrings, dorsiflexors and plantar flexors, functional training, static strength training for central stabilizers ( Core); group 3, which will perform low intensity strength training (20% of 1RM) associated with RFS (TFRFS) and group 4, which will perform aerobic training (40% of reserve heart rate) associated with RFS (TARFS). The RFS pressure used in the protocols of groups 3 and 4 will be between 60 to 80% of the arterial occlusion pressure of the lower limb. OA patients will be submitted to interventions for a period of 12 weeks, with a frequency of twice a week and an interval of 72 hours between them. The measures of maximum dynamic strength in the leg press exercise (1RM), the cross-sectional area of ??the rectus femoris (ASTRF) and vastus lateralis (ASTVL) muscles, functionality tests, range of motion and pain perception will be performed before, after 4, 8 and 12 weeks. The mixed model with repeated measures will be used to analyze the variables of interest with a significance level set at p <0.05.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-12-20
• Study Completion: 2022-04-30
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients of both sexes, aged over 60 years, functional independence, diagnosed with knee osteoarthritis; patients with medical referral for physical therapy treatment; absence of severe cardiovascular or musculoskeletal diseases

Exclusion Criteria

Patients with knee arthroplasty, contraindication for the use of pressure cuffs or tourniquets, with peripheral vascular disease, who use anticoagulants, will be excluded; history of deep vein thrombosis, congenital lower limb malformations, diagnosis of fibromyalgia; contraindication to exercise

Study & Design

• Study Type: Intervention
• Study Design: Not specified