A Comparative evaluation of anaesthetic efficacy of buccal infiltration with 4% Articaine v/s conventional 2% Lignocaine with 1:100,000 adrenaline for extraction of maxillary anterior teeth : A split-mouth study
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- To evaluate and compare the anaesthetic efficacy of ‘4% articaine’ and ‘2% lignocaine’ with buccal infiltration in bilateral maxillary tooth indicated for extraction
研究概览
简要总结
-Effective control of pain during dental procedures has been one of the most important prerequisite of dentistry.Local anesthesia is used to reduce pain while performing the extraction of teeth.
-Many patients avoid dental extractions due to painful injection. In the present-day dental practice, Providing treatment with least amount of pain and discomfort is the key.
Extraction of maxillary teeth require buccal and palatal infiltration of anesthetic drug And Palatal infiltration is often painful and patients are likely to be uncooperative
-Articaine, synthesized in 1975, has been widely used since. In contrast to lignocaine, it has a higher tissue diffusion rate and lower toxicit****y and it is 1.5times more potent than lignocaine with shortest elimination half-life (42min) making it the currently safest option.
-Hence, the current study will be conducted to evaluate the anesthetic efficacy of articaine versus Lignocaine in extraction of maxillary anteriors, the necessity of giving a palatal infiltration in addition to buccal infiltrationbuccal infiltration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient indicated for extraction of bilateral permanent anterior maxillary tooth Including Premolars(from left premolar to right premolar tooth) -Symptomatic and firm maxillary anterior tooth indicated for extraction.
- •Patients with ASA status I and having normal bleeding & clotting time.
- •Patient requiring therapeutic tooth extraction for orthodontic purpose.
排除标准
- •Patients allergic to anaesthetic agent -Patient with periodontally compromised permanent maxillary anterior tooth including premolar (excluding central incisor) -Patient with systemic co-morbidities .
- •Pregnancy -Lactating female subjects.
- •Patients who have any pathologies at the extraction site.( Example: cyst, odontomes., etc).
结局指标
主要结局
To evaluate and compare the anaesthetic efficacy of ‘4% articaine’ and ‘2% lignocaine’ with buccal infiltration in bilateral maxillary tooth indicated for extraction
时间窗: on the same day during & after the procedure at interval of 4-6hours
and Need for palatal Injection to be given
时间窗: on the same day during & after the procedure at interval of 4-6hours
次要结局
- To evaluate onset, duration & depth of anesthesia & peri operative pain assesment(on the same day during & after the procedure at interval of 4-6hours)
研究者
DR MANJIRI JIVANRAO NAKADE
KLE V.K. Institute of Dental Sciences