A multi-omics approach to modeling disease mechanisms in frontotemporal dementia
- Conditions
- frontotemporal dementia10029305
- Registration Number
- NL-OMON54408
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
- Diagnosed with non-genetic Frontotemporal Dementia, diagnosed by a physician
at the Alzheimercentrum Amsterdam (AmsterdamUMC locatie VUmc and;
Registered at the Dutch Brain Bank (Nederlandse Hersenbank) to donate their
brains when they decease
- Diagnosed with genetic frontotemporal dementia
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded
from participation in this study:
- Contra-indication to perform a skin biopsy (known cause for prolonged
bleeding, high risk of infection)
- No cerebral spine fluid biomaterial or biomarker results available to exclude
co-existing Alzheimer pathology
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method