A randomized, double blind, comparative study of vitamin D3 versus placebo in patients with Parkinson disease aged between 45 and 85 years old to improve neurological signs and quality of life
Not Applicable
- Conditions
- Parkinson disease
- Registration Number
- JPRN-UMIN000001841
- Lead Sponsor
- Jikei University School of Medicine
- Brief Summary
Vitamin D3 supplementation may stabilize PD for a short period in patients with FokI TT or CT genotypes without triggering hypercalcemia, although this effect may be nonspecific for PD. This trial was registered at UMIN Clinical Trials Registry as UMIN000001841.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Not provided
Exclusion Criteria
1. Already taking vitamin D supplement or 1,25 vitamin D 2. History of kidney stone 3. Familial or early onset (< 55 years old) type of Parkinson disease 4. Osteoporosis 5. Other difficulties judged by the physician in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method changes of UPDRS, HY stage, MMSE
- Secondary Outcome Measures
Name Time Method changes of PDQ-39 and EQ-5D