The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients

Not Applicable

Recruiting

• Conditions: Female Pattern Hair Loss; Platelet-rich Fibrin; Platelet-Rich Plasma

• Registration Number: NCT06440655
• Lead Sponsor: Siriraj Hospital

Brief Summary

The goal of this clinical trial is to compare between platelet-rich fibrin and platelet-rich plasma in female pattern hair loss . The main question\[s\] it aims to answer are:

* efficacy between platelet-rich fibrin and platelet-rich plasma

* safety between platelet-rich fibrin and platelet-rich plasma Participants will be divided into 2 side of treatment with composed of

1. Platelet rich plasma

2. Platelet rich fibrin

Detailed Description

Subject was treated both platelet-rich fibrin and platelet-rich plasma for 3 times which 1 month interval then will be followed up at 4 months and 6 months after last treatment

Study Timeline

• Study Start: 2023-05-30
• Study First Submitted: 2024-02-06
• Status Verified: 2024-05
• Study First Submitted QC: 2024-05-27
• Last Update Submitted: 2024-05-27
• Study First Posted: 2024-06-04
• Last Update Posted: 2024-06-04
• Primary Completion: 2024-06-30
• Study Completion: 2024-09-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 10

Inclusion Criteria

• Age 20-55 years
• Female
• Subject who was diagnosed with Female pattern hair loss in Ludwig Classification 2 (part width 2-4 centimeters) by Dermatologist

Exclusion Criteria

• Pregnancy or Lactation subjects
• Subject with history of platelet dysfunction, low platelet, anemia, cirrhosis, cancer, or immunocompromised host
• Subject who are active smoking and alcoholism
• Subject who has dermatitis, scar or infection at intervention area
• Subject who has history of allergy to anesthesia drug
• Subject who taking NSAIDs, Hormonal drug, anticoagulants drug
• Subject who has psychiatric condition diagnosed by psychiatrist
• Subject who are not allowed to take a photo

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Trichoscan	baseline(week0), 4 months after last treatment(week20), 6 months after last treatment(week28)	Average counts and density of hair per 1.5mm\^2

Secondary Outcome Measures

Name	Time	Method
Visual analog scale	baseline(week0), 1 month after first treatment(week4), 1 months after second treatment(week8)	pain during intervention
The 7-point of doctor subjective global assessment	baseline(week0),1 month after first treatment(week4), 1 months after second treatment(week8), 4 months after last treatment(week20), 6 months after last treatment(week28)	Evaluation of improvement through picture by doctor
The 7-point of patient subjective global assessment	baseline(week0),1 month after first treatment(week4), 1 months after second treatment(week8), 4 months after last treatment(week20), 6 months after last treatment(week28)	Evaluation of improvement through picture by patient

Trial Locations

Locations (2)

Faculty of Medicine Siriraj Hospital, Mahidol University; 🇹🇭 Bangkok Noi, Bangkok, Thailand

Medicine Siriraj Hospital, Mahidol University; 🇹🇭 Bangkok Noi, Bangkok, Thailand