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The Most Effective Treatment Strategy for Diabetic Macular Edema.

Suspended
Conditions
Diabetic macular edema
Registration Number
NL-OMON25771
Lead Sponsor
The Rotterdam Eye Hospital / Rotterdam Ophthalmic InstitutePO Box 70030, NL-3000 LM Rotterdam
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Suspended
Sex
Not specified
Target Recruitment
456
Inclusion Criteria

1. Age ¡Ý 18 years;

2. Able to read and sign the written informed consent;

Exclusion Criteria

1. Previous laser photocoagulation therapy within the last 6 months;

2. Previous anti-VEGF therapy (Avastin, Lucentis, Eylea, or any investigational anti-VEGF drug) within the last 3 months;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Proportion of treatment failures at 72 weeks, with treatment failure defined at 24 weeks as < 50 micron decrease in CFT and no improvement in VA, i.e. 1 or more letters loss in VA, compared to baseline. After the 24 week visit failure of treatment is defined as > 50 micron increase in CFT, irrespective of VA, compared to week 24.
Secondary Outcome Measures
NameTimeMethod
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