Effects of Long Term Physical Training Once a Week on Fitness and Quality of Life in Elderly Asthmatics
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Maximum oxygen uptake
研究概览
简要总结
This controlled study is undertaken to investigate the effects of a long term outpatient training program on physical fitness and quality of life in elderly asthmatics.
详细描述
Physical training is well known to support a healthy lifestyle. Patients with asthma are often unnecessarily restricted of physical activities or avoid exercise due to the unpleasant experience of exercise-induced dyspnea. As a consequence both children and adults with asthma are less fit than their peers. Like in healthy individuals, regular training supports health in asthmatics. In short-term training programs improvements of physical capabilities have been achieved in children and young adults with asthma. Programs of longer durations than 3 months have not been published in controlled trials. Effects of exercise training on quality of life in adult asthmatics are lacking.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •physician diagnosed asthma
- •non-smoker
- •stable condition
- •informed consent
排除标准
- •participation in pulmonary rehabilitation in the past 12 months prior to study inclusion
- •unability to attend training sessions on a regular basis for one year
- •symptomatic coronary heart disease
- •uncontrolled heart failure
- •hemodynamically relevant cardiac rhythm disorders
- •hemodynamically relevant cardiac valvular disorders
- •uncontrolled arterial hypertension
- •hypercapnic respiratory failure
- •severe hypoxemia (i.e. PaO2 <50 mm Hg resp. SaO2 <80% at rest)
- •history of decompensated right heart failure
- •pulmonary arterial hypertension (PA mean pressure at rest >20 mm Hg)
- •severe osteoporosis
- •severe airway obstruction (FEV1 <50% predicted, FEV1 <60% predicted following bronchodilatation)
- •maximum work rate of less than 50 watt during ergometer testing
- •uncontrolled asthma
- •COPD exacerbation
- •severe adipositas (BMI >35 kg/m2)
结局指标
主要结局
Maximum oxygen uptake
时间窗: One year
Maximum oxygen uptake measured during unsteady state cycle ergometer test with work increments of 10 watts each minute until exhaustion.
次要结局
- General quality of life(One year)
- Disease-specific quality of life(One year)